Obesity is defined as the presence of excessive adiposity which presents a health risk. In present days, obesity has reached pandemic proportions and is considered to be a threat to public health. Why is this happening? How did we get here? What can we do to maintain a healthy weight? In this video, we offer a simple explanation of how our body controls of how the organism controls our metabolism, and our appetite.

Obesity is not only characterized by excessive adiposity but also by the dysregulation of the organism's ability to keep the body weight stable (weight homeostasis). Weight homeostasis is achieved by maintaining an equilibrium between energy intake (how much we eat) and energy consumption (our metabolism). This video provides a brief overview of the food intake cycle, a key regulator of weight homeostasis, as it controls how much we eat.

In this video, we will explore the hormonal mediators of hunger, satiation, and satiety, and uncover the key differences between individuals with normal weight and obesity. Our bodies are equipped with a complex network of neural and hormonal signals that work together to keep our food intake in balance. These signals influence our appetite, food preferences, and the frequency of our meals. We'll delve into the hormonal superstars like ghrelin, leptin, insulin, and others that play a significant role in hunger and satiety. We will also shed light on the hormonal differences between individuals with normal weight and those with obesity. Understanding these differences is crucial in unraveling the mysteries of obesity and how our hormonal imbalance can contribute to weight gain and difficulties in weight management. Join us as we delve into the fascinating world of appetite regulation, hormones, and their impact on obesity. Get ready for an enlightening journey!

In this video, we will delve into the fascinating effects of orexigenic and anorexigenic hormones on the brain. Additionally, we will explore the key pathophysiological processes underlying obesity, providing -what we hope to be - valuable insights into this complex condition. Orexigenic hormones, often referred to as "appetite-stimulating" hormones, play a role in increasing our desire to eat. These hormones, such as ghrelin, stimulate hunger signals in the brain, influencing our food intake. On the other hand, anorexigenic hormones, known as "appetite-suppressing" hormones, help regulate our food intake by promoting feelings of fullness and satiety. Hormones like leptin and peptide YY (PYY) act as powerful satiety signals in the brain, sending messages that curb our appetite and contribute to the termination of eating episodes. We invite you to explore the differences concerning the brain regulation of food intake and energy expenditure, between people with normal weight and obese individuals.